Medicinal Chemistry: The Molecular Basis of Drug Discovery - Davidson CollegeedX
Was lernen Sie in diesem Kurs?
This medicinal chemistry course explores how chemists modify a molecule’s structure to design a safe and effective drug. This course opens with a brief history of drug discovery and introduces the modern drug approval process. Then, we will transition to learning about receptors and enzymes, the body’s molecules most often targeted by drugs. We will also discuss the topics of pharmacokinetics (drug adsorption, elimination, and half-life) and metabolism. The course closes with units on how potential drug molecules are identified and subsequently optimized into safe and effective drugs.
Teacher:Erland Stevens Erland Stevens earned his Ph.D. from the University of Michigan at Ann Arbor in 1997 under Will Pearson in the area of nitrogen heterocycles. He then pursued postdoctoral studies at The Scripps Research Institute with K. Barry Sharpless. In 1998 Stevens joined the chemistry faculty at Davidson College. He regularly teaches medicinal chemistry to junior and senior undergraduates. In 2006 and 2007 Stevens taught in the continuing education program at the Research Triangle Park site of GlaxoSmithKline. He recently completed a textbook, Medicinal Chemistry: The Modern Drug Discovery Process, published by Pearson Education. Stevens' lab studies the synthesis and activity of antiviral nucleoside analogues.